Absolute quantification accuracy
Convenient calibration with the IONICON LCU
PTR-TOFMS provides absolute quantitative analysis in real-time. However, to obtain high accuracy concentration values, rapid and easy-to-use calibration of certain compounds in e-liquids can be very handy. Particularly, the main components of e-liquids, PG and VG, tend to fragment upon ionization via proton transfer from H3O+. Although relative concentration measurement results (e.g. puff-by-puff variations) are not affected by this phenomenon, absolute concentration values should be corrected for the fragmentation ratios.
With IONICON's Liquid Calibration Unit (LCU) liquid standards are brought into the gas phase at well-defined concentrations for direct analysis with a PTR-TOFMS instrument. There is no need to purchase expensive liquid standards, but the user can easily mix home-made standards by dissolving defined amounts of pure substances in water or hexane.
Because of full automation of the LCU and the PTR-TOFMS control software, calibration curves can be acquired without the user being present during the measurement, thus saving valuable working hours. In addition to correcting the concentration values of PG and VG, with the LCU also the accuracy of all other important constituents (e.g. nicotine, flavor and aroma compounds, etc.) can be brought to perfection.