Radboud University - Life Science Trace Detection Laboratory (TDLab)

PTR-TOF 8000

Affiliation: Radboud University - Life Science Trace Detection Laboratory (TDLab), The Netherlands
IONICON instrument: PTR-TOF 8000
Contact person: Dr. Simona M. Cristescu

Why is an IONICON PTR-MS very well suited for your measurement tasks?

The PTR-TOF 8000 we mainly use for exhaled breath analysis. The excellent sensitivity of the instrument allows us to characterize and monitor in real-time changes in the exhaled VOC profile induced by e.g. dietary intake (SCFAs) or prolonged exercise. This gives us information on metabolic changes within the human body in a non-invasive manner

Dr. Cristescu

Most relevant scientific papers and conference presentations:

Henderson, B.; Lopes Batista, G.; Bertinetto, C.G.; Meurs, J.; Materić, D.; Bongers, C.C.W.G.; Allard, N.A.E.; Eijsvogels, T.M.H.; Holzinger, R.; Harren, F.J.M.; et al. Exhaled Breath Reflects Prolonged Exercise and Statin Use during a Field Campaign. Metabolites 2021, 11, 192,
doi:10.3390/metabo11040192

Henderson, B.; Meurs, J.; Lamers, C.R.; Batista, G.L.; Materić, D.; Bertinetto, C.G.; Bongers, C.C.W.G.; Holzinger, R.; Harren, F.J.M.; Jansen, J.J.; et al. Non-Invasive Monitoring of Inflammation in Inflammatory Bowel Disease Patients during Prolonged Exercise via Exhaled Breath Volatile Organic Compounds. Metabolites 2022, 12, 224,
doi:10.3390/METABO12030224

Meurs, J.; Sakkoula, E.; Cristescu, S. Real-time non-invasive monitoring of short-chain fatty acids in exhaled breath. Front. Chem. 2022, 424,
doi:10.3389/FCHEM.2022.853541