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Scientific Articles - PTR-MS Bibliography

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[Schmidberger2013] Schmidberger, T.., R.. Gutmann, and R.. Huber, "Application of PTR-MS in mammalian cell culture", 6th International PTR-MS Conference on Proton Transfer Reaction Mass Spectrometry and Its Applications, pp. 39, 2013.
Mass spectrometry is a well-known technology to detect O2 and CO2 in the off-gas of cell culture fermentations. In contrast to classical spectrometers, the proton transfer reaction mass spectrometer (PTR-MS) applies a very soft ionization strategy and therefore the spectra show less fragments and are easier to interpret. In our study we applied the PTR-MS technology to monitor volatile organic compounds (VOC) in mammalian cell culture processes. Interesting masses were identified and correlations between PTR-MS data and off-line parameters will be presented.
[Gutmann2012] Gutmann, R.., M.. Luchner, J.. Herbig, A.. Hansel, K.. Bayer, and G.. Striedner, "Advanced bioprocess monitoring by implementation of Proton Transfer Reaction - Mass Spectrometry (PTR-MS) for measurement of volatile components in the bioreactor", ACIB, Book of abstracts, vol. -, pp. -, 2012.

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Selected PTR-MS related Reviews

F. Biasioli, C. Yeretzian, F. Gasperi, T. D. Märk: PTR-MS monitoring of VOCs and BVOCs in food science and technology, Trends in Analytical Chemistry 30 (7) (2011).

J. de Gouw, C. Warneke, T. Karl, G. Eerdekens, C. van der Veen, R. Fall: Measurement of Volatile Organic Compounds in the Earth's Atmosphere using Proton-Transfer-Reaction Mass Spectrometry. Mass Spectrometry Reviews, 26 (2007), 223-257.

W. Lindinger, A. Hansel, A. Jordan: Proton-transfer-reaction mass spectrometry (PTR–MS): on-line monitoring of volatile organic compounds at pptv levels, Chem. Soc. Rev. 27 (1998), 347-375.


Lists with PTR-MS relevant publications of the University of Innsbruck can be found here: Atmospheric and indoor air chemistry, IMR, Environmental Physics and Nano-Bio-Physics


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