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Scientific Articles - PTR-MS Bibliography

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Filters: Author is Colard, Stephane  [Clear All Filters]
[1688] Breiev, K., K. M. M. Burseg, G. OConnell, E. Hartungen, S. S. Biel, X. Cahours, S. Colard, T. D. Maerk, and P. Sulzer, "An online method for the analysis of volatile organic compounds in electronic cigarette aerosol based on proton transfer reaction mass spectrometry", Rapid Commun. Mass Spectrom., vol. 30, pp. 691–697, Feb, 2016.
<p>Rationale Due to the recent rapid increase in electronic cigarette (e-cigarette) use worldwide, there is a strong scientific but also practical interest in analyzing e-cigarette aerosols. Most studies to date have used standardized but time-consuming offline technologies. Here a proof-of-concept for a fast online quantification setup based on proton transfer reaction mass spectrometry (PTR-MS) is presented. Methods The combination of a novel sampling interface with a time-of-flight PTR-MS instrument specially designed for three scenarios is introduced: (i) mainstream aerosol analysis (aerosol that the user inhales prior to exhalation), and analysis of exhaled breath following (ii) mouth-hold (no inhalation) and (iii) inhalation of e-cigarette aerosols. A double-stage dilution setup allows the various concentration ranges in these scenarios to be accessed. Results First, the instrument is calibrated for the three principal constituents of the e-cigarettes&#39; liquids, namely propylene glycol, vegetable glycerol and nicotine. With the double-stage dilution the instrument&#39;s dynamic range was easily adapted to cover the concentration ranges obtained in the three scenarios: 20&ndash;1100 ppmv for the mainstream aerosol characterisation; 4&ndash;300 ppmv for the mouth-hold; and 2 ppbv to 20 ppmv for the inhalation experiment. Conclusions It is demonstrated that the novel setup enables fast, high time resolution e-cigarette studies with online quantification. This enables the analysis and understanding of any puff-by-puff variations in e-cigarette aerosols. Large-scale studies involving a high number of volunteers will benefit from considerably higher sample throughput and shorter data processing times.</p>

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Selected PTR-MS related Reviews

F. Biasioli, C. Yeretzian, F. Gasperi, T. D. Märk: PTR-MS monitoring of VOCs and BVOCs in food science and technology, Trends in Analytical Chemistry 30 (7) (2011).

J. de Gouw, C. Warneke, T. Karl, G. Eerdekens, C. van der Veen, R. Fall: Measurement of Volatile Organic Compounds in the Earth's Atmosphere using Proton-Transfer-Reaction Mass Spectrometry. Mass Spectrometry Reviews, 26 (2007), 223-257.

W. Lindinger, A. Hansel, A. Jordan: Proton-transfer-reaction mass spectrometry (PTR–MS): on-line monitoring of volatile organic compounds at pptv levels, Chem. Soc. Rev. 27 (1998), 347-375.


Lists with PTR-MS relevant publications of the University of Innsbruck can be found here: Atmospheric and indoor air chemistry, IMR, Environmental Physics and Nano-Bio-Physics


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