The world's leading PTR-MS company

Ultra-Sensitive Real-Time Trace Gas Analyzers  •  Modular TOF-MS for Research & OEM

Ultimate Performance in mass resolution, sensitivity and detection limits
The future of performance: from the smallest and most affordable PTR-TOF 1000 to our new flagship PTR-TOF 6000 X2, the IONICON PTR-TOFMS series is leading the field. Benefit from our experience and know how!
PTR-QMS Performance Data
Market-leading online detection limits for VOCs reaching ppqv-level with ULTRA-PURE ion source. The best available detection limits for online trace gas analysis now also with H3O+, NO+ and O2+ as precursor ions.
The Analyzer for your Analytical Instrument
Quadrupole or time-of-flight mass spectrometer Since 1998 IONICON produces and develops PTR-MS instruments. Nowadays nearly all our analytical instruments are based on a TOF-MS. Learn why and decide what type of detector is the best for your analytical objective. Here are some tips which might help you to decide what type of detector is the best for your analytical objective:


"We are studying VOCs and their chemistry in the atmosphere. These VOCs from various sources are often present in very low concentrations therefore we need an instrument with a low detection limit. One important part of our research is the biosphere atmosphere interaction. We measure e.g. plants emissions. Plants emit a wide variety of VOCs which demands an analyzer able to cover a broad mass range in a short period of time. The IONICON PTR-TOF 4000 allows for simultaneous measurements of many VOCs with high sensitivity at high temporal resolution."
“The acquisition of a Proton Transfer Reaction Mass Spectrometry (PTR-MS) represents an expansion of the current instrumental facilities of the VOC laboratory. The PTR-MS will provide the laboratory with extended capabilities in terms of long-term reliability and extreme sensitivity, which are necessary for the implementation of VOC-based breath tests within clinical practice.”
"During the past two decades, the continued development of IONICON PTRMS systems has led to a steady advancement of our research capabilities resulting in important scientific discoveries as well as providing a large share of the biosphere-atmosphere VOC exchange measurements we have used as the basis for developing VOC emission models for air quality and climate models. In addition to the outstanding performance of their instruments, the excellent support and collaborative environment at IONICON have been critical to the success of our research program."


Close to 50 users gathered in Innsbruck for the 2019 PTR-TOF training. We reached out to the steadily growing base of IONICON instrument users in fall 2018, announcing the 2019 “hands-on” PTR-MS training course and the 3rd IONICON User-Day. The response was overwhelming and after receiving close to 50 applications, we had to close the […]

Up to 3x increased sensitivity, a better LoD and 10% higher resolution The IONICON PTR-TOF success story continues also in 2019 and starts with a performance upgrade for our PTR-TOF series. Continuous investments in R&D lead to a series of improvements of our hexapole Ion-Guide technology as well as the implementation of new RF-electronics catering […]


E. Pallozzi, G. Guidolottia, P. Ciccioli, F. Brilli, S. Feil, C. Calfapietra: "Does the novel fast-GC coupled with PTR-TOF-MS allow a significant advancement in detecting VOC emissions from plants?", Agricultural and Forest Meteorology, 216, 2016.
G. O’Connell, S. Colard, K. Breiev, P. Sulzer, S. S. Biel, X. Cahours, J. D. Pritchard, K. M.M. Burseg: "An Experimental Method to Determine the Concentration of Nicotine in Exhaled Breath and its Retention Rate Following Use of an Electronic Cigarette", J Environ Anal Chem 2: 161, 2015.
4. - 8. February 2019
The PTR-MS community gathers in Innsbruck - home of PTR-MS
1. - 4. February 2019
Join us for the next IONICON PTR-TOFMS training seminar!