The world's leading PTR-MS company

Ultra-Sensitive Real-Time Trace Gas Analyzers  •  Modular TOF-MS for Research & OEM

Ultimate Performance in mass resolution, sensitivity and detection limits
The future of performance: from the smallest and most affordable PTR-TOF 1000 to our new flagship PTR-TOF 6000 X2, the IONICON PTR-TOFMS series is leading the field. Benefit from our experience and know how!
An Evolution that Resulted in Perfection
From SIFT to advanced PTR-MS technology and ultimate performance PTR-TOF trace gas analyzers
PTR-QMS Performance Data
Market-leading online detection limits for VOCs reaching ppqv-level with ULTRA-PURE ion source. The best available detection limits for online trace gas analysis now also with H3O+, NO+ and O2+ as precursor ions.


"We are studying VOCs and their chemistry in the atmosphere. These VOCs from various sources are often present in very low concentrations therefore we need an instrument with a low detection limit. One important part of our research is the biosphere atmosphere interaction. We measure e.g. plants emissions. Plants emit a wide variety of VOCs which demands an analyzer able to cover a broad mass range in a short period of time. The IONICON PTR-TOF 4000 allows for simultaneous measurements of many VOCs with high sensitivity at high temporal resolution."
“The acquisition of a Proton Transfer Reaction Mass Spectrometry (PTR-MS) represents an expansion of the current instrumental facilities of the VOC laboratory. The PTR-MS will provide the laboratory with extended capabilities in terms of long-term reliability and extreme sensitivity, which are necessary for the implementation of VOC-based breath tests within clinical practice.”
"During the past two decades, the continued development of IONICON PTRMS systems has led to a steady advancement of our research capabilities resulting in important scientific discoveries as well as providing a large share of the biosphere-atmosphere VOC exchange measurements we have used as the basis for developing VOC emission models for air quality and climate models. In addition to the outstanding performance of their instruments, the excellent support and collaborative environment at IONICON have been critical to the success of our research program."


Crucial application benefits from fast switching NH4+ ionization The proprietary and IONICON exclusive method of producing NH4+ solely from H2O vapor and N2 in the established hollow cathode ion source, without the need of any ammonia (PCT application submitted) has many advantages. Today we would like to introduce a promising application field where NH4+ is the […]

A novel proprietary method of NH4+ production for IONICON customers In PTR-TOF-MS traditionally H3O+ reagent ions produced from H2O vapor are used. NH4+ reagent ions have been mentioned in literature as being particularly beneficial because of higher sensitivity (less fragmentation) and higher selectivity (higher proton affinity). However, so far toxic and corrosive ammonia was needed […]


D. Materić, M. Lanza, P. Sulzer, J. Herbig, D. Bruhn, V. Gauci, N. Mason, C. Turner: "Selective Reagent Ion-Time of Flight-Mass Spectrometry study of six common monoterpenes", International Journal of Mass Spectrometry, available online 9 June 2017.
K. Breiev, K. M. M. Burseg, G. O'Connell, E. Hartungen, S. S. Biel, X. Cahours, S. Colard, T. D. Märk, P. Sulzer: "An online method for the analysis of volatile organic compounds in electronic cigarette aerosol based on proton transfer reaction mass spectrometry", Rapid Commun. Mass Spectrom., 30: 691–697, 2016.
Resources and downloads
Below you will find past events. Visit our dedicated microsites for downloads or more information about a particular event.
8. - 11. September 2019
We're a proud sponsor of the International Association of Breath Research conference 2019. Join us!