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Scientific Articles - PTR-MS Bibliography

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Found 3 results
Title [ Year(Asc)]
Filters: Author is A. Jordan  [Clear All Filters]
[1441] Jordan, A., S.. Haidacher, G.. Hanel, E.. Hartungen, J. Herbig, L.. Märk, R.. Schottkowsky, H.. Seehauser, P.. Sulzer, and T.D.. Märk, "An online ultra-high sensitivity Proton-transfer-reaction mass-spectrometer combined with switchable reagent ion capability (PTR + SRI−MS)", International Journal of Mass Spectrometry, vol. 286, pp. 32 - 38, 2009.
<div>Proton-transfer-reaction mass-spectrometry (PTR-MS) developed in the</div> <div>1990s is used today in a wide range of scientific and technical fields.</div> <div>PTR-MS allows for real-time, online determination of absolute concentrations</div> <div>of volatile (organic) compounds (VOCs) in air with high sensitivity</div> <div>(into the low pptv range) and a fast response time (in the 40&ndash;100 ms</div> <div>time regime). Most PTR-MS instruments employed so far use an ion</div> <div>source consisting of a hollow cathode (HC) discharge in water vapour</div> <div>which provides an intense source of proton donor H3O+ ions. As the</div> <div>use of other ions, e.g. NO+ and O2+, can be useful for the identification</div> <div>of \{VOCs\} and for the detection of \{VOCs\} with proton affinities</div> <div>(PA) below that of H2O, selected ion flow tube mass spectrometry</div> <div>(SIFT-MS) with mass selected ions has been applied in these instances.</div> <div>SIFT-MS suffers, however, from at least two orders lower reagent</div> <div>ion counts rates and therefore SIFT-MS suffers from lower sensitivity</div> <div>than PTR-MS. Here we report the development of a PTR-MS instrument</div> <div>using a modified \{HC\} ion source and drift tube design, which allows</div> <div>for the easy and fast switching between H3O+, NO+ and O2+ ions produced</div> <div>in high purity and in large quantities in this source. This instrument</div> <div>is capable of measuring low concentrations (with detection limits</div> <div>approaching the ppqv regime) of \{VOCs\} using any of the three reagent</div> <div>ions investigated in this study. Therefore this instrument combines</div> <div>the advantages of the PTR-MS technology (the superior sensitivity)</div> <div>with those of SIFT-MS (detection of \{VOCs\} with \{PAs\} smaller</div> <div>than that of the water molecule and the capability to distinguish</div> <div>between isomeric compounds). We will first discuss the setup of this</div> <div>new PTR+SRI-MS mass spectrometer instrument, its performance for</div> <div>aromates, aldehydes and ketones (with a sensitivity of up to nearly</div> <div>1000 cps/ppbv and a detection limit of about several 100&amp;#xa0;ppqv)</div> <div>and finally give some examples concerning the ability to distinguish</div> <div>structural isomeric compounds.&nbsp;</div>
[Lindinger1998a] Lindinger, W., A. Hansel, and A. Jordan, "On-line monitoring of volatile organic compounds at pptv levels by means of proton-transfer-reaction mass spectrometry (PTR-MS) medical applications, food control and environmental research", International Journal of Mass Spectrometry and Ion Processes, vol. 173, no. 3, pp. 191 - 241, 1998.
A proton transfer reaction mass spectrometer (PTR-MS) system has been developed which allows for on-line measurements of trace components with concentrations as low as a few pptv. The method is based on reactions of H3O+ ions, which perform non-dissociative proton transfer to most of the common volatile organic compounds (VOCs) but do not react with any of the components present in clean air. Medical applications by means of breath analysis allow for monitoring of metabolic processes in the human body, and examples of food research are discussed on the basis of VOC emissions from fruit, coffee and meat. Environmental applications include investigations of VOC emissions from decaying biomatter which have been found to be an important source for tropospheric acetone, methanol and ethanol. On-line monitoring of the diurnal variations of VOCs in the troposphere yield data demonstrating the present sensitivity of PTR-MS to be in the range of a few pptv. Finally, PTR-MS has proven to be an ideal tool to measure Henry's law constants and their dependencies on temperature as well as on the salt content of water.
[Hansel1995] Hansel, A., A. Jordan, R. Holzinger, P. Prazeller, W. Vogel, and W. Lindinger, "Proton transfer reaction mass spectrometry: on-line trace gas analysis at the ppb level", International Journal of Mass Spectrometry and Ion Processes, vol. 149-150, pp. 609 - 619, 1995.
A system for trace gas analysis using proton transfer reaction mass spectrometry (PTR-MS) has been developed which allows for on-line measurements of components with concentrations as low as 1 ppb. The method is based on reactions of H3O+ ions, which perform non-dissociative proton transfer to most of the common organic trace constituents but do not react with any of the components present in clean air. Examples of analysis of breath taken from smokers and non-smokers as well as from patients suffering from cirrhosis of the liver, and of air in buildings as well as of ambient air taken at a road crossing demonstrate the wide range of applicability of this method. An enhanced level of acetonitrile in the breath is a most suitable indicator that a person is a smoker. Enhanced levels of propanol strongly indicate that a person has a severe liver deficiency.

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Selected PTR-MS related Reviews

F. Biasioli, C. Yeretzian, F. Gasperi, T. D. Märk: PTR-MS monitoring of VOCs and BVOCs in food science and technology, Trends in Analytical Chemistry 30 (7) (2011).

J. de Gouw, C. Warneke, T. Karl, G. Eerdekens, C. van der Veen, R. Fall: Measurement of Volatile Organic Compounds in the Earth's Atmosphere using Proton-Transfer-Reaction Mass Spectrometry. Mass Spectrometry Reviews, 26 (2007), 223-257.

W. Lindinger, A. Hansel, A. Jordan: Proton-transfer-reaction mass spectrometry (PTR–MS): on-line monitoring of volatile organic compounds at pptv levels, Chem. Soc. Rev. 27 (1998), 347-375.


Lists with PTR-MS relevant publications of the University of Innsbruck can be found here: Atmospheric and indoor air chemistry, IMR, Environmental Physics and Nano-Bio-Physics


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