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The world's leading PTR-MS company

Providing ultra-sensitive solutions for real-time trace gas analysis since 1998


Proton Transfer Reaction - Mass Spectrometers

We offer solutions for online VOC monitoring and real-time trace gas detection. Robust, fast, accurate and extremely sensitive we satisfy the highest claims for the world's best scientists. Have a look at our PTR-MS product range and find your instrument!

Our Trace Calibration Product Range

Precise calibration is essential for most analytical instruments. We offer systems that provide controlled amounts of calibration gas, zero air or even standards from evaporated liquids. Browse our range of LCU systems.

Analytical instruments and monitoring solutions

We are developing individual analytical instruments and industrial monitoring solutions according to our customers' needs for more than a decade. Benefit from our scientific and engineering expertise!


Proton Transfer Reaction - Mass Spectrometry
PTR-MS (Proton Transfer Reaction – Mass Spectrometry) is the benchmark method for simultaneous real-time monitoring of volatile (organic) compounds (VOCs) without sample preparation in very low concentrations. We're the market-leading PTR-MS company.
Selective Reagent Ionization - Mass Spectrometry
SRI-MS is a new technology where the user can select from different reagent ions for chemical ionization direct injection mass spectrometry, only available from IONICON. Our expertise as the world's leading PTR-MS company lead to the development of new ionization technologies currently including H3O+, O2+, NO+, Kr+ or Xe+ as selective reagent ions.
IONICON ion funnel technology
Benefit from the ION BOOSTER technology with up to 10x increased sensitivity! Optionally available for selected new PTR-MS systems and as upgrade for many existing instruments.


"Our group uses Ionicon PTR-MS and PTR-QiTOF instruments to study the sources, chemistry, and impacts of atmospheric organic compounds across a diverse range of environments. We use these instruments because the combination of sensitivity, mass resolution, and fast time response provides an important toolset for our research."
"At Wageningen UR we see many research applications for the IONICON PTR-QiTOF. It’s easy use, sensitivity, accuracy and on line detection without the need of prior treatments makes it a high potential instrument for all kinds of diagnostic and quality oriented research, going from environmental issues, to food and to health biomarkers."
"We use IONICON PTR-MS and PTR-TOFMS instruments for real-time measurements of a broad array of VOCs in the atmosphere, including ecosystem and aircraft scale flux measurements, direct emissions from plants and microbial cultures, controlled laboratory oxidation studies of VOC reactions and secondary aerosol formation, and field studies of atmospheric chemistry and air pollution. The rapid response and low detection limits made possible by these instruments are critical to our scientific investigations."


IONICON’s PTR-TOFMS technology has become the leading method for real-time breath gas analysis. The International Association for Breath Research (IABR) held its annual summit conference at the renowned ETH Zürich in Switzerland. Between September 14 – 16, 2016, the latest scientific results in breath research were presented. In 12 talks researchers featured PTR-MS as their tool of […]

We at IONICON are proudly celebrating this achievement During the last days of September 2016 we finished the construction of PTR-MS instrument No. 300. It’s a PTR-TOF 1000 that we built for an overseas customer who will use it for analyzing chemical pollutants in industrial areas. Our team took some pride and special care when loading it […]


K. Breiev, K. M. M. Burseg, G. O'Connell, E. Hartungen, S. S. Biel, X. Cahours, S. Colard, T. D. Märk, P. Sulzer: "An online method for the analysis of volatile organic compounds in electronic cigarette aerosol based on proton transfer reaction mass spectrometry", Rapid Commun. Mass Spectrom., 30: 691–697, 2016.
E. Pallozzi, G. Guidolottia, P. Ciccioli, F. Brilli, S. Feil, C. Calfapietra: "Does the novel fast-GC coupled with PTR-TOF-MS allow a significant advancement in detecting VOC emissions from plants?", Agricultural and Forest Meteorology, 216, 2016.
14. - 16. September 2016
We're a proud sponsor of the International Association of Breath Research conference 2016
26. - 30. September 2016
We're a proud sponsor of the International Global Atmospheric Chemistry (IGAC) Project 2016 Science Conference in Breckenridge, CO, USA.